Medical disclaimer: CalmVerdict summarizes what people say about supplements on Reddit. It is not medical advice, and nothing here is meant to diagnose, treat, cure, or prevent any disease. These statements have not been evaluated by the Food and Drug Administration. Talk to your doctor or pharmacist before starting a supplement, especially if you take an antidepressant or other medicine, are pregnant, or have a medical condition. Do not stop or change prescribed medicine on your own. If you are in crisis or thinking about suicide, call or text 988 (US) or your local emergency number. Full disclaimer.

What people with stress, anxiety and low mood actually report about supplements

We read 373,690 Reddit comments from r/Anxiety, r/Nootropics, r/Stress, r/Supplements, r/depression_help, r/insomnia, r/sleep (May 2026 to October 2026), kept 2,191 from people who say they used a supplement, and scored 26 ingredients. Every quote links to its source, and every fact links to NIH or PubMed.

26ingredients tracked
2,191owner comments
1,283with a clear rating
7concerns ranked

Browse all supplements Find by concern

Highest-rated by Reddit owners

Ranked by CalmVerdict score (Bayesian owner sentiment, recommendations and tolerability). Vitamin D and B vitamins are background pages, not ranked.

Passionflower illustration
Calming herbs

Passionflower

4.0 (19 owner comments)
Taste & formCalming effect

“A mix of magnesium glycinate, Ltheanine and passion flower has helped me the most in terms of supplements.”

What owners report →
L-theanine illustration
Amino acids & precursors

L-theanine

4.0 (330 owner comments)
Calming effectSide effects

“The I found a liquid L theanine and that made all the difference in the world.”

What owners report →
Magnesium glycinate illustration
Magnesium

Magnesium glycinate

4.0 (370 owner comments)
Calming effectSide effects

“Magnesium glycinate, improved my sleep, fewer muscle twitches, and helped me feel less tension etc.”

What owners report →
Chamomile illustration
Calming herbs

Chamomile

4.0 (44 owner comments)
Taste & formCalming effect

“I mix it (it tastes sweet) with chamomile tea before bed.”

What owners report →

Most discussed on Reddit

By concern

Anxiety & worry

20 supplements ranked

Low mood

13 supplements ranked

Everyday stress

11 supplements ranked

Panic attacks

7 supplements ranked

Rumination & intrusive thoughts

7 supplements ranked

Physical tension

4 supplements ranked

PMS & PMDD mood

3 supplements ranked

Popular comparisons

Guides

Background pages: Vitamin D3, B-complex / B vitamins. CalmVerdict does not score prescription drugs. Adaptogens such as ashwagandha and rhodiola are not scored here; they will be covered on adaptogenic.ai (coming soon).